Lee Gilyeo Cancer and Diabetes Institute (LCDI) in Gacheon Medical School and Korean Bioinformation Center (KOBIC) in KRIBB jointly sequenced a full length Korean genome. This project was carried out by sharing tasks between the two teams. LCDI performed sequencing experiment and KOBIC analyzed the genome sequence. This is a model project in Korea that makes synergy effect by collaboration between different research areas. The KOREF genome sequence came from Dr. Kim Sungjin who is the director of LCDI. The two teams will keep working on his genome to produce a high quality Asian reference genome that can be used as the basis for personalize medicine.

     
  KOREF Genome's Phylogenetic Mapping Single Nucleotide Polymorphism: SNP GeVab  
 

Present humans are known to be originated from Africa 150,000 years ago. Using the whole genome information we located the phylogenetic branch of the Korean.

  

It is known that 99.99% of the DNA bases among people are the same. Remaining 0.1%, around 3 million bases, determine the genetic and phenotypic differences among people such as eye color, skin color, and susceptability to diseases. Among the variations found in a population, 90% of them are caused by one single base change. This is called SNP. Scientists think that it is possible to develop personalized medicine by researching on SNPs.

 
 

The genome map shows the genomic information such as some genes or some mutations are on some location.
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Users can download KOREF genome sequence and the related information of our project. We hope that sharing KOREF genome information helps biologist's researches and attracts people into genomics world.
 
   
  The Outline of KOREF Genome Analysis      
 

By comparing the 2003 Caucasian genome sequence stored in NCBI, we found that KOREF genome sequence covers 98.35% of the NCBI's.